Assistant Professor
Ohio State University
Division of Gastroenterology, Hepatology and Nutrition, Columbus, OH 43210
shanlin.ke@osumc.edu |
ke.229@osu.edu
The human microbiome comprises bacteria, archaea, viruses, and eukaryotes which reside in or on our bodies. These organisms impact human physiology, both in health and in disease, contributing to the enhancement or impairment of metabolic and immune functions. Our lab specializes in bioinformatics and machine learning approaches to analyze the human microbiome data.
Host-microbiota interactions are the complex chemical and signaling processes between the body's cells and tiny microbes that live in/on it. These interactions are essential for the body's overall health. Our lab aims to leverage state-of-the-art computational approaches, multi-omics data, and human cohorts to gain deeper insights into these intricate relationships.
We aim to translate microbiome research into clinical applications by developing microbiome-based therapeutics. Our work involves identifying beneficial microbial strains, engineering probiotics, and testing novel microbial interventions for pancreatic diseases.
